COVID-19 vaccine is 90-percent effective: Pfizer and BioNTech


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Pfizer Inc says its experimental COVID-19 vaccine is more than 90-percent effective, a major victory in the fight against a pandemic that has killed more than a million people, battered the world’s economy, and upended daily life.
Pfizer and German partner BioNTech SE are the first drugmakers to release successful data from a large-scale clinical trial of a coronavirus vaccine. The companies said they have so far found no serious safety concerns and expect to seek US authorisation this month for emergency use of the vaccine for people aged 16 to 85.
If authorised, the number of doses will initially be limited and many questions remain, including how long the vaccine will provide protection. However, the news provides hope that other COVID-19 vaccines in development may also prove effective.
“Today is a great day for science and humanity,” Albert Bourla, Pfizer’s chairman and chief executive, said.
“We are reaching this critical milestone in our vaccine development programme at a time when the world needs it most with infection rates setting new records, hospitals nearing over-capacity and economies struggling to reopen.”
For Pfizer to seek US authorisation for emergency use of its vaccine, it will need two months of safety data from about half the study’s 44,000 participants, which is expected late this month.
The MSCI index of world stock markets hit a record high following the announcement. Pfizer shares were indicated 6 percent higher in New York, while BioNTech’s US stock leapt 18 percent.
“I’m near ecstatic,” Bill Gruber, one of Pfizer’s top vaccine scientists, said in an interview. “This is a great day for public health and for the potential to get us all out of the circumstances we’re now in.”
Pfizer and BioNTech have a $1.95bn contract with the US government to deliver 100 million vaccine doses beginning this year. They have also reached supply agreements with the European Union, the United Kingdom, Canada and Japan.
To save time, the companies began manufacturing the vaccine before they knew whether it would be effective. They now expect to produce up to 50 million doses, or enough to protect 25 million people this year.
Pfizer said it expects to produce up to 1.3 billion doses of the vaccine in 2021.
The US pharmaceutical giant said the interim analysis was conducted after 94 participants in the trial developed COVID-19, examining how many of them had received the vaccine versus a placebo.
The company did not break down exactly how many of those who fell ill received the vaccine. Still, more than 90 percent effectiveness implies that no more than eight of the 94 people who caught COVID-19 had been given the vaccine, which was administered in two shots about three weeks apart.
The efficacy rate is well above the 50-percent effectiveness required by the US Food and Drug Administration for a coronavirus vaccine.
To confirm the efficacy rate, Pfizer said it would continue the trial until there are 164 COVID-19 cases among participants. Given the recent spike in US infection rates, that number could be reached by early December, Gruber said.
The data have yet to be peer-reviewed or published in a medical journal. Pfizer said it would do so once it has results from the entire trial.
The global race for a vaccine has seen wealthier countries forge multibillion-dollar supply deals with drugmakers like Pfizer, AstraZeneca Plc and Johnson & Johnson, raising questions over when middle income and poorer nations will get access to inoculations.
The US’s quest for a vaccine has been the Trump administration’s central response to the pandemic. The US has the world’s highest known number of COVID-19 cases and deaths, with more than 10 million infections and over 237,000 fatalities.
President Donald Trump repeatedly assured the public that his administration would likely identify a successful vaccine in time for the presidential election, held last Tuesday. On Saturday, Democratic rival Joe Biden was declared the winner.
Vaccines are seen as essential tools to help end the health crisis that has shuttered businesses and left millions out of work. Millions of children whose schools were closed in March remain in remote learning programmes.
Dozens of drugmakers and research groups around the globe have been racing to develop vaccines against COVID-19, which on Sunday exceeded 50 million infections since the new coronavirus was first recorded late last year in China.
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Triển lãm ảnh 90 năm lịch sử Mặt trận tổ quốc Việt Nam


Triển lãm ảnh 90 năm lịch sử Mặt trận tổ quốc Việt Nam
Triển lãm ảnh 90 năm lịch sử Mặt trận tổ quốc Việt Nam Thứ Hai, ngày 9/11/2020 – 16:12 (PLO)- Triển lãm với gần 100 bức ảnh là những tư liệu quý phản ánh rõ nét dấu ấn quan trọng của Mặt trận Tquốc Việt Nam và các lực lượng yêu nước qua các thời kỳ.


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Amanda Seyfried’s “toughest challenge” was getting through school.
The ‘Mamma Mia’ actress – who has three-year-old daughter Nina with husband Thomas Sadoski – was bullied by her classmates so found her teenage years difficult, but she was always aware the difficult times wouldn’t last forever.
She said: “The toughest challenge I’ve faced was school. It was tough and I was bullied, but it doesn’t last forever…
“I wish I could tell my 16-year-old self don’t listen to mean girls! They’re just there to make you feel bad and the truth is they feel bad about themselves too – that’s why they do it.”
Despite her years of career success, the 32-year-old star believes her family will always be her “greatest achievement” and she insisted they always come first.
She added: “My family will always be my greatest achievement. If you put your family first then I’ve always said you’re heading in the right direction.”
Amanda lives on a farm and though she’s devoted to all her animals, her beloved dog Finn will always hold a special place in her heart.
In a recent interview, she said: “People aside, my most treasured possession is my dog Finn. He was a rescue dog and, even though he will probably never totally understand, he changed my life in more ways than he’ll ever know. I’m so grateful to him.”
The ‘Mean Girls’ star is very “spiritual” and loves being outdoors and “at one” with nature.
She explained: “I’m a spiritual person and I practice mindfulness. I like yoga, I believe in alternative medicine and I enjoy being at one with nature.
“I feel so safe when I’m at home. We live in a quiet place where there’s nothing Hollywood about it.”
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Watch Philip Rivers make woeful attempt to tackle Chuck Clark


Watch Philip Rivers make woeful attempt to tackle Chuck
Watch. Ravens Watch Philip Rivers make woeful attempt to tackle Chuck Clark / by Kevin Brown Ravens There are only two starting quarterbacks older than Philip Rivers in the NFL. Late in the first quarter against the Ravens on Sunday, Rivers’ age was on full display as he tried to prevent a Ravens’ defensive touchdown as safety Chuck Clark


Watch Philip Rivers make woeful attempt to tackle Chuck Clark
Watch Philip Rivers make woeful attempt to tackle Chuck Clark originally appeared on NBC Sports Washington. There are only two starting quarterbacks older than Philip Rivers in the NFL. Late in …


Watch Philip Rivers Make Woeful Attempt to Tackle Chuck
Watch Philip Rivers make woeful attempt to tackle Chuck Clark originally appeared on NBC Sports Washington. There are only two starting quarterbacks older than Philip Rivers in the NFL. Late in …


Watch Colts’ Philip Rivers Submit Worst Tackle Attempt In …
Philip Rivers is facing a week’s worth of embarrassing memes. And, honestly, he deserves it. The Indianapolis Colts quarterback submitted a preposterously poor tackle attempt Sunday afternoon …


Watch: Flopping Philip Rivers takes abuse on social media
Watch: Flopping Philip Rivers takes abuse on social media … get a look at Philip Rivers’ flop that led to Clark’s hurdle. … Philip Rivers with the worst tackle attempt since the merger.


WATCH: Philip Rivers makes hilarious tackle attempt | News …
Poor Philip Rivers never stood a chance against the turf at Lucas Oil Stadium, tripping over his own feet while trying to position himself to make a tackle on Chuck Clark. Clark hopped over Rivers, who flailed in vein to try and make an arm tackle, on his way to a touchdown that tied the game, 7-7.


NFL: Philip Rivers attempts, fails at tackling
Rivers tried to tackle the Ravens’ Chuck Clark. It … didn’t fare well. … Watch; Philip Rivers’ failed tackle attempt might rival Daniel Jones’ stumble for worst 2020 QB play.


Must See: Rivers makes hilariously bad tackle attempt on …
After rookie RB Jonathan Taylor fumbled, Colts QB Philip Rivers attempts to make a tackle on Ravens safety Chuck Clark but falls and allows him to leap right over him and run into the end zone for …


WATCH: Philip Rivers makes hilarious tackle attempt
Indianapolis Colts quarterback Philip Rivers went viral on Sunday for a hilarious failed tackle attempt. With the Colts leading 7-0 in the first quarter, Rivers handed off to rookie running back


Colts’ Philip Rivers makes hilarious attempt at a tackle
Pardon Philip Rivers for not being the most mobile quarterback in the world, especially at the age of 38. Rivers made a tackle attempt many football fans can relate to late in the first quarter of …
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Premier League hits and misses: Can Leicester City go all …
Leicester look the real deal – can they keep it up? 2:53 FREE TO WATCH: Highlights from Leicester’s win over Wolves in the Premier League.


Not one more of us will be sacrificed
Independent SAGE said: “We fear that the government has given up trying to control the pandemic further and is hoping that by reacting to local outbreaks as and when they happen (e.g. the current Leicester lockdown), it can keep levels of infection at what they regard as a ‘manageable level’ (i.e. their current quite high but not …


Leicester agree Welford Road stadium naming rights for …
Leicester Tigers’ home ground is to be rebranded Mattioli Woods Welford Road in a five-year deal that will assist the club’s drive to survive the coronavirus pandemic. It is the first time …


What happens next for Leicester City in the transfer …
‘They believe in me’ – Leicester City loanee proves why he has been given new deal; Read More Related Articles. Where Wesley Fofana fits, Demarai Gray’s future – fans’ Leicester City questions …


Leicester City: Why we are all rooting for the Foxes – BBC …
Match of the Day host Gary Lineker made what is beginning to look like a rash promise after Leicester beat champions Chelsea 2-1 in December Ranieri ‘wants to kill’ Flores They win without even …


Leeds United 1-4 Leicester City: Foxes move within a point …
Leeds were more urgent – Dallas picking up a yellow card for an overly aggressive tackle on Marc Albrighton, while the coaching staff encouraged quick throw-ins to keep the intensity up. But Leeds …


‘You’ll see who Slimani is’ – Leicester outcast opens up …
Leicester City forward Islam Slimani has opened up on his move to Monaco last season and felt that “no-one believed” in him upon his arrival at the Ligue One club. The forward had a productive …


5 Ways Real Estate Agents Deceive Their Seller Clients
They only come in after you reduce it again – when it looks like too good a deal to pass up. History shows us over and over again that homes priced correctly from day one sell for the most money. In fact, in a strong seller’s market, you may wind up getting multiple offers that end up over asking price.


Top 10 Dirty Tricks Used by Real Estate Agents
So basically, the agent can manipulate these reports to fit any price he/she wants. Oh and keep in mind, once the agent runs the report for the client the comparable sales they have excluded won’t show up at all in the generated report. THE PAYOFF: Manipulate the pricing in whatever direction to close the deal.


15 Secrets No Real Estate Broker Will Tell You – This Old …
“People turn up to get a sense of the market or the neighborhood, but they are not ready to buy.” They tend to sign in, tour the place and then take off with the agent’s business card in hand. The agent makes an effort to keep in touch with these some-day buyers, in hopes of closing a deal down the line. “My Commission Is Negotiable.”
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